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However, it does have to be de-methylated back to morphine (in the liver) to expert its analgesic properties

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McNeil took its case all the way to the FDA commissioner, who turned down the company's final appeal, saying the agency had "refuted each example to respond to your allegation." McNeil did not respond directly to questions about its opposition to the campaign.But it stressed that it had launched numerous acetaminophen safety education efforts, both on its own and with industry and government partners

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